Vol 363, Issue 6426
Introduction to special issue
Essays on Science and Society
This Week in Science
Products & Materials
Books et al.
The rhomboid protein fold accelerates diffusion-limited intramembrane proteolysis by modulating membrane viscosity.
- Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition
A small-molecule inhibitor selectively kills mycobacteria by targeting a pathway that a countering enzyme makes vulnerable.
- Identification of site-specific isotopic labels by vibrational spectroscopy in the electron microscope
Shifts in the C–O vibration of alanine with electron energy-loss spectroscopy enable nanoscale isotopic mapping.
Quasi-periodic oscillations in x-ray observations of a tidal disruption event indicate a rapidly spinning supermassive black hole.
When mice sense serious danger, serotonin neurons switch their activity from movement suppression to movement facilitation.