Vol 363, Issue 6424
This Week in Science
Products & Materials
Books et al.
Obesity caused by loss of function of one gene copy can be rescued via CRISPR-mediated activation of the normal copy.
A model encompassing multiple conformations of chiral phosphoric acid catalysts accurately predicts enantioselectivities.
Combined expansion and lattice light-sheet microscopy enables high-speed nanoscale molecular imaging of neural circuits.
Targeting ligand-to-metal instead of metal-to-ligand charge transfer extends iron’s photoactivity to a nanosecond time frame.
Transient weakly associated complexes between a K atom and a NaK molecule have been observed at ultracold temperatures.
A route to two marine natural products distinct from the biosynthesis enables structural diversification for drug discovery.
Studies of pollinators and crops suggest that phylogenetic loss is not equivalent to species loss in agricultural systems.
- Flagellar microtubule doublet assembly in vitro reveals a regulatory role of tubulin C-terminal tails
Inherent interaction properties of tubulin provide a structural basis for flagellar microtubule doublet assembly.
Transfer of strain-specific antibodies after bone marrow transplant prevents cytomelagovirus reactivation in the recipient.
H3K9me3-marked heterochromatin is deployed early in development but removed later for cell type–specific gene expression.