Subject: PLOS Genetics Volume 14(12) December 2018 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: 8bit

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New Articles in PLOS Genetics

PUBLISHED: December 01, 2018 to December 31, 2018

Editorial

Doubling down on forensic twin studies

Topic Page

Micropeptide

Perspective

R-loops modulate Trypanosome antigenic variation

Viewpoints

BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2

Review

Population structure in genetic studies: Confounding factors and mixed models

Research Articles

Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis

Ancestral origin of ApoE epsilon 4 Alzheimer disease risk in Puerto Rican and African American populations

Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds

Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo

The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/beta -catenin signaling through a Dvl dependent mechanism

De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders

RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation

Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability

Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility

Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex

Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence

Interhomolog polymorphism shapes meiotic crossover within the Arabidopsis RAC1 and RPP13 disease resistance genes

regQTLs: Single nucleotide polymorphisms that modulate microRNA regulation of gene expression in tumors

Evolution of maternal and zygotic mRNA complements in the early Drosophila embryo

miR-3607-3p suppresses non-small cell lung cancer (NSCLC) by targeting TGFBR1 and CCNE2

beta -actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprograming

The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea

Expression reflects population structure

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

RSM1, an Arabidopsis MYB protein, interacts with HY5/HYH to modulate seed germination and seedling development in response to abscisic acid and salinity

AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

Distinguishing genetically between the germlines of male monozygotic twins

Genetic exchanges are more frequent in bacteria encoding capsules

Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling

Regulation of pollen lipid body biogenesis by MAP kinases and downstream WRKY transcription factors in Arabidopsis

Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers

Gene expression variation and parental allele inheritance in a Xiphophorus interspecies hybridization model

Comprehensive cross-disorder analyses of CNTNAP2 suggest it is unlikely to be a primary risk gene for psychiatric disorders

On the unfounded enthusiasm for soft selective sweeps II: Examining recent evidence from humans, flies, and viruses

Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity

Diversification of DNA binding specificities enabled SREBP transcription regulators to expand the repertoire of cellular functions that they govern in fungi

Bayesian multiple logistic regression for case-control GWAS

Corrections

Correction: Association analysis using somatic mutations

Correction: Within-patient mutation frequencies reveal fitness costs of CpG dinucleotides and drastic amino acid changes in HIV

Correction: Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice

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