New Articles in PLOS Genetics

PUBLISHED: January 01, 2018 to January 31, 2018

Reviews

Aging and the rise of somatic cancer-associated mutations in normal tissues

Rosa Ana Risques, Scott R. Kennedy

Taking cohesin and condensin in context

Kobe C. Yuen, Jennifer L. Gerton

Research Articles

A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects

Julia E. Draper, Patrycja Sroczynska, Muhammad Z. H. Fadlullah, Rahima Patel, Gillian Newton, Wolfgang Breitwieser, Valerie Kouskoff, Georges Lacaud

Regulation of circadian clock transcriptional output by CLOCK:BMAL1

Alexandra J. Trott, Jerome S. Menet

AKAP200 promotes Notch stability by protecting it from Cbl/lysosome-mediated degradation in Drosophila melanogaster

Neeta Bala Tannan, Giovanna Collu, Ashley C. Humphries, Ekatherina Serysheva, Ursula Weber, Marek Mlodzik

An Ichor-dependent apical extracellular matrix regulates seamless tube shape and integrity

Jeffrey B. Rosa, Mark M. Metzstein, Amin S. Ghabrial

Genome wide comparison of Ethiopian Leishmania donovani strains reveals differences potentially related to parasite survival

Arie Zackay, James A. Cotton, Mandy Sanders, Asrat Hailu, Abedelmajeed Nasereddin, Alon Warburg, Charles L. Jaffe

Cdc73 suppresses genome instability by mediating telomere homeostasis

Rahul V. Nene, Christopher D. Putnam, Bin-Zhong Li, Katarina G. Nguyen, Anjana Srivatsan, Christopher S. Campbell, Arshad Desai, Richard D. Kolodner

Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure

Janek Salatzki, Anna Foryst-Ludwig, Kajetan Bentele, Annelie Blumrich, Elia Smeir, Zsofia Ban, Sarah Brix, Jana Grune, Niklas Beyhoff, Robert Klopfleisch, Sebastian Dunst, Michal A. Surma, Christian Klose, Michael Rothe, Frank R. Heinzel, Alexander Krannich, Erin E. Kershaw, Dieter Beule, P. Christian Schulze, Nikolaus Marx, Ulrich Kintscher

Glass promotes the differentiation of neuronal and non-neuronal cell types in the Drosophila eye

Carolyn A. Morrison, Hao Chen, Tiffany Cook, Stuart Brown, Jessica E. Treisman

Brassinosteroids regulate root growth by controlling reactive oxygen species homeostasis and dual effect on ethylene synthesis in Arabidopsis

Bingsheng Lv, Huiyu Tian, Feng Zhang, Jiajia Liu, Songchong Lu, Mingyi Bai, Chuanyou Li, Zhaojun Ding

Filling gaps in bacterial amino acid biosynthesis pathways with high-throughput genetics

Morgan N. Price, Grant M. Zane, Jennifer V. Kuehl, Ryan A. Melnyk, Judy D. Wall, Adam M. Deutschbauer, Adam P. Arkin

Ovule identity mediated by pre-mRNA processing in Arabidopsis

EncarnaciÃ³n RodrÃguez-Cazorla, Samanta OrtuÃ±o-Miquel, HÃ©ctor Candela, Lindsay J. Bailey-Steinitz, Martin F. Yanofsky, Antonio MartÃnez-Laborda, Juan-JosÃ© Ripoll, Antonio Vera

Identification of an elaborate NK-specific system regulating HLA-C expression

Hongchuan Li, Martin A. Ivarsson, Victoria E. Walker-Sperling, Jeff Subleski, Jenna K. Johnson, Paul W. Wright, Mary Carrington, Niklas K. BjÃ¶rkstrÃ¶m, Daniel W. McVicar, Stephen K. Anderson

MORC2B is essential for meiotic progression and fertility

Baolu Shi, Jiangyang Xue, Jian Zhou, Seth D. Kasowitz, Yuanwei Zhang, Guanxiang Liang, Yongjuan Guan, Qinghua Shi, Mingxi Liu, Jiahao Sha, Xiaoyan Huang, P. Jeremy Wang

Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans

Selma S. Alkafeef, Clinton Yu, Lan Huang, Haoping Liu

The impact of ribosomal interference, codon usage, and exit tunnel interactions on translation elongation rate variation

Khanh Dao Duc, Yun S. Song

Differentially-dimensioned furrow formation by zygotic gene expression and the MBT

Yi Xie, J. Todd Blankenship

6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related protein TTR-33

Sarah-Lena Offenburger, Xue Yan Ho, Theresa Tachie-Menson, Sean Coakley, Massimo A. Hilliard, Anton Gartner

Mutations in Caenorhabditis elegans neuroligin-like glit-1, the apoptosis pathway and the calcium chaperone crt-1 increase dopaminergic neurodegeneration after 6-OHDA treatment

Sarah-Lena Offenburger, Elisabeth Jongsma, Anton Gartner

Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers

Daniel P. Hollern, Matthew R. Swiatnicki, Eran R. Andrechek

A HAD family phosphatase CSP-6 regulates the circadian output pathway in Neurospora crassa

Xiaoying Zhou, Bin Wang, Jillian M. Emerson, Carol S. Ringelberg, Scott A. Gerber, Jennifer J. Loros, Jay C. Dunlap

DNA polymerase IV primarily operates outside of DNA replication forks in Escherichia coli

Sarah S. Henrikus, Elizabeth A. Wood, John P. McDonald, Michael M. Cox, Roger Woodgate, Myron F. Goodman, Antoine M. van Oijen, Andrew Robinson

Allocation of distinct organ fates from a precursor field requires a shift in expression and function of gene regulatory networks

Sneha Palliyil, Jinjin Zhu, Luke R. Baker, Sarah D. Neuman, Arash Bashirullah, Justin P. Kumar

The Arabidopsis SUMO E3 ligase SIZ1 mediates the temperature dependent trade-off between plant immunity and growth

Valentin Hammoudi, Like Fokkens, Bas Beerens, Georgios Vlachakis, Sayantani Chatterjee, Manuel Arroyo-Mateos, Paul F. K. Wackers, Martijs J. Jonker, Harrold A. van den Burg

Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide

Julienne C. Kaiser, Alyssa N. King, Jason C. Grigg, Jessica R. Sheldon, David R. Edgell, Michael E. P. Murphy, Shaun R. Brinsmade, David E. Heinrichs

Compound heterozygous loss-of-function mutations in KIF20A are associated with a novel lethal congenital cardiomyopathy in two siblings

Jacoba J. Louw, Ricardo Nunes Bastos, Xiaowen Chen, CÃ©line Verdood, Anniek Corveleyn, Yaojuan Jia, Jeroen Breckpot, Marc Gewillig, Hilde Peeters, Massimo M. Santoro, Francis Barr, Koenraad Devriendt

Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila

Yasufumi Sakakibara, Michiko Sekiya, Naoki Fujisaki, Xiuming Quan, Koichi M. Iijima

Signalling crosstalk during early tumorigenesis in the absence of Polycomb silencing

Jorge V. Beira, Joana Torres, Renato Paro

Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay

Olivier Duverger, Jenna C. Carlson, Chelsea M. Karacz, Mary E. Schwartz, Michael A. Cross, Mary L. Marazita, John R. Shaffer, Maria I. Morasso

Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity

Montserrat Torres-Oliva, Julia Schneider, Gordon Wiegleb, Felix Kaufholz, Nico Posnien

Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites

Xiao P. Peng, Shelly Lim, Shibai Li, Lisette Marjavaara, Andrei Chabes, Xiaolan Zhao

Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions

Zuchra Zakirova, Tomas Fanutza, Justine Bonet, Ben Readhead, Weijia Zhang, Zhengzi Yi, Genevieve Beauvais, Thomas P. Zwaka, Laurie J. Ozelius, Robert D. Blitzer, Pedro Gonzalez-Alegre, Michelle E. Ehrlich

HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression

Alix Warburton, Catherine J. Redmond, Katharine E. Dooley, Haiqing Fu, Maura L. Gillison, Keiko Akagi, David E. Symer, Mirit I. Aladjem, Alison A. McBride

CRL4 antagonizes SCF^Fbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory

Tianyu Song, Shenghui Liang, Jiye Liu, Tingyue Zhang, Yifei Yin, Chenlu Geng, Shaobing Gao, Yan Feng, Hao Xu, Dongqing Guo, Amanda Roberts, Yuchun Gu, Yong Cang

A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila

Maitreyi Upadhyay, Michael Kuna, Sara Tudor, Yesenia Martino Cortez, Prashanth Rangan

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

Rebecca King, Felix L. Struebing, Ying Li, Jiaxing Wang, Allison Ashley Koch, Jessica N. Cooke Bailey, Puya Gharahkhani, International Glaucoma Genetics Consortium , NEIGHBORHOOD Consortium , Stuart MacGregor, R. Rand Allingham, Michael A. Hauser, Janey L. Wiggs, Eldon E. Geisert

Insular Celtic population structure and genomic footprints of migration

Ross P. Byrne, Rui Martiniano, Lara M. Cassidy, Matthew Carrigan, Garrett Hellenthal, Orla Hardiman, Daniel G. Bradley, Russell L. McLaughlin

Kinesin Khc-73/KIF13B modulates retrograde BMP signaling by influencing endosomal dynamics at the Drosophila neuromuscular junction

Edward H. Liao, Lindsay Gray, Kazuya Tsurudome, Wassim El Mounzer, Fatima Elazzouzi, Christopher Baim, Sarah Farzin, Mario R. Calderon, Grant Kauwe, A. Pejmun Haghighi

Identifying and exploiting trait-relevant tissues with multiple functional annotations in genome-wide association studies

Xingjie Hao, Ping Zeng, Shujun Zhang, Xiang Zhou

WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity

TomÃ¡Å¡ PrÃ¡t, Jakub HajnÃ½, Wim Grunewald, Mina Vasileva, Gergely MolnÃ¡r, Ricardo Tejos, Markus Schmid, Michael Sauer, JiÅ™Ã Friml

The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization

Sandra Korge, Bert Maier, Franziska BrÃ¼ning, Lea Ehrhardt, Thomas Korte, Matthias Mann, Andreas Herrmann, Maria S. Robles, Achim Kramer

Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies

Lori L. O'Brien, Qiuyu Guo, Emad Bahrami-Samani, Joo-Seop Park, Sean M. Hasso, Young-Jin Lee, Alan Fang, Albert D. Kim, Jinjin Guo, Trudy M. Hong, Kevin A. Peterson, Scott Lozanoff, Ramya Raviram, Bing Ren, Ben Fogelgren, Andrew D. Smith, Anton Valouev, Andrew P. McMahon

Rewired RNAi-mediated genome surveillance in house dust mites

Mosharrof Mondal, Pavel Klimov, Alex Sutton Flynt

MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6

Bastian Stielow, Florian Finkernagel, Thorsten Stiewe, Andrea Nist, Guntram Suske

Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania

Matt Ravenhall, Susana Campino, Nuno SepÃºlveda, Alphaxard Manjurano, Behzad Nadjm, George Mtove, Hannah Wangai, Caroline Maxwell, Raimos Olomi, Hugh Reyburn, Christopher J. Drakeley, Eleanor M. Riley, Taane G. Clark, in collaboration with MalariaGEN

Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism

Inferring sex-specific demographic history from SNP data

Florian Clemente, Mathieu Gautier, Renaud Vitalis

Analysis of bacterial genomes from an evolution experiment with horizontal gene transfer shows that recombination can sometimes overwhelm selection

Rohan Maddamsetti, Richard E. Lenski

Coordination of olfactory receptor choice with guidance receptor expression and function in olfactory sensory neurons

Puneet Dang, Stephen A. Fisher, Derek Stefanik, Junhyong Kim, Jonathan A. Raper

Corrections

Correction: High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop

Chenxi Qiu, Olivia C. Erinne, Jui M. Dave, Ping Cui, Huiyan Jin, Nandhini Muthukrishnan, Leung K. Tang, Sabareesh Ganesh Babu, Kenny C. Lam, Paul J. Vandeventer, Ralf Strohner, Jan Van den Brulle, Sing-Hoi Sze, Craig D. Kaplan

Correction: Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain

Kai Wang, Ruijuan Xu, Jennifer Schrandt, Prithvi Shah, Yong Z. Gong, Chet Preston, Louis Wang, Jae Kyo Yi, Chih-Li Lin, Wei Sun, Demetri D. Spyropoulos, Soyoung Rhee, Mingsong Li, Jie Zhou, Shaoyu Ge, Guofeng Zhang, Ashley J. Snider, Yusuf A. Hannun, Lina M. Obeid, Cungui Mao

Correction: Investigating the case of human nose shape and climate adaptation

Arslan A. Zaidi, Brooke C. Mattern, Peter Claes, Brian McEvoy, Cris Hughes, Mark D. Shriver

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