Subject: PLOS Computational Biology Volume 14(6) June 2018 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: 8bit

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New Articles in PLOS Computational Biology

PUBLISHED: June 01, 2018 to June 29, 2018

Messages from ISCB

2018 ISCB Overton Prize awarded to Cole Trapnell

2018 ISCB Innovator Award recognizes M. Madan Babu

Education

Cloud computing applications for biomedical science: A perspective

Research Articles

Instance-based generalization for human judgments about uncertainty

Assessment of ab initio models of protein complexes by molecular dynamics

The role of intracellular signaling in the stripe formation in engineered Escherichia coli populations

Bridging structure and function: A model of sequence learning and prediction in primary visual cortex

Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain

Latent environment allocation of microbial community data

Limits on reliable information flows through stochastic populations

In vivo and in silico dynamics of the development of Metabolic Syndrome

Temporal precision of regulated gene expression

Predicting 3D structure and stability of RNA pseudoknots in monovalent and divalent ion solutions

Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates

Anticipating epidemic transitions with imperfect data

Mechanical positioning of multiple nuclei in muscle cells

φ-evo: A program to evolve phenotypic models of biological networks

The effect of cell geometry on polarization in budding yeast

Changes in parasite traits, rather than intensity, affect the dynamics of infection under external perturbation

3D morphology-based clustering and simulation of human pyramidal cell dendritic spines

Identifying functional groups among the diverse, recombining antigenic var genes of the malaria parasite Plasmodium falciparum from a local community in Ghana

A biophysical mechanism for preferred direction enhancement in fly motion vision

Hybrid stochastic framework predicts efficacy of prophylaxis against HIV: An example with different dolutegravir prophylaxis schemes

Mechanical evolution of DNA double-strand breaks in the nucleosome

Nonmechanistic forecasts of seasonal influenza with iterative one-week-ahead distributions

Tellurium notebooks'An environment for reproducible dynamical modeling in systems biology

Classification of red blood cell shapes in flow using outlier tolerant machine learning

Evolution of chemokine receptors is driven by mutations in the sodium binding site

Modeling the functions of condensin in chromosome shaping and segregation

Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response

Evolutionary dynamics of paroxysmal nocturnal hemoglobinuria

Stochastic shielding and edge importance for Markov chains with timescale separation

Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer

Control of neurite growth and guidance by an inhibitory cell-body signal

Solving the RNA design problem with reinforcement learning

Community interactions and spatial structure shape selection on antibiotic resistant lineages

Transmission of temporally correlated spike trains through synapses with short-term depression

Lipidated apolipoprotein E4 structure and its receptor binding mechanism determined by a combined cross-linking coupled to mass spectrometry and molecular dynamics approach

Removing contaminants from databases of draft genomes

The impact of temporal sampling resolution on parameter inference for biological transport models

Exploring the single-cell RNA-seq analysis landscape with the scRNA-tools database

Age density patterns in patients medical conditions: A clustering approach

Thalamocortical and intracortical laminar connectivity determines sleep spindle properties

Two critical positions in zinc finger domains are heavily mutated in three human cancer types

Computation predicts rapidly adapting mechanotransduction currents cannot account for tactile encoding in Merkel cell-neurite complexes

Correction

Correction: A Mixture of Delta-Rules Approximation to Bayesian Inference in Change-Point Problems

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