Subject: PLOS Computational Biology Volume 14(3) March 2018 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: 8bit


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New Articles in PLOS Computational Biology

PUBLISHED: March 01, 2018 to March 30, 2018


Ten simple rules for collaborative lesson development

Ten simple rules to create a serious game, illustrated with examples from structural biology

PLOS Computational Biology 2017 Reviewer and Editorial Board Thank You


Meet-U: Educating through research immersion

A FAIR guide for data providers to maximise sharing of human genomic data

Eleven quick tips for running an interdisciplinary short course for new graduate students

Eleven quick tips for architecting biomedical informatics workflows with cloud computing

Research Articles

Receptor recharge time drastically reduces the number of captured particles

speaq 2.0: A complete workflow for high-throughput 1D NMR spectra processing and quantification

An evolutionary learning and network approach to identifying key metabolites for osteoarthritis

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease

Inverse tissue mechanics of cell monolayer expansion

Increased T cell trafficking as adjunct therapy for HIV-1

Classifying dynamic transitions in high dimensional neural mass models: A random forest approach

An entropic barriers diffusion theory of decision-making in multiple alternative tasks

Population-specific design of de-immunized protein biotherapeutics

Cytosolic proteins can exploit membrane localization to trigger functional assembly

Factors affecting basket catheter detection of real and phantom rotors in the atria: A computational study

Free energy profiles for unwrapping the outer superhelical turn of nucleosomal DNA

A computational model for how cells choose temporal or spatial sensing during chemotaxis

Deploying digital health data to optimize influenza surveillance at national and local scales

Method for the simulation of blood platelet shape and its evolution during activation

Stoichiometric balance of protein copy numbers is measurable and functionally significant in a protein-protein interaction network for yeast endocytosis

Bat detective'Deep learning tools for bat acoustic signal detection

Neuronal gain modulability is determined by dendritic morphology: A computational optogenetic study

4Cin: A computational pipeline for 3D genome modeling and virtual Hi-C analyses from 4C data

The importance of geometry in the corneal micropocket angiogenesis assay

Use of temperature to improve West Nile virus forecasts

ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy

Gap junction plasticity as a mechanism to regulate network-wide oscillations

LAILAPS-QSM: A RESTful API and JAVA library for semantic query suggestions

Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state

Closely related, yet unique: Distinct homo- and heterodimerization patterns of G protein coupled chemokine receptors and their fine-tuning by cholesterol

Across-subjects classification of stimulus modality from human MEG high frequency activity

Particle-based simulations of polarity establishment reveal stochastic promotion of Turing pattern formation

In silico study of multicellular automaticity of heterogeneous cardiac cell monolayers: Effects of automaticity strength and structural linear anisotropy

iDREM: Interactive visualization of dynamic regulatory networks

Imbalanced amplification: A mechanism of amplification and suppression from local imbalance of excitation and inhibition in cortical circuits

Epigenetic regulation of cell fate reprogramming in aging and disease: A predictive computational model

The exclusive effects of chaperonin on the behavior of proteins with 52 knot

The Pathway Coexpression Network: Revealing pathway relationships

Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells

Role of genetic heterogeneity in determining the epidemiological severity of H1N1 influenza

Activation gating in HCN2 channels

Model-based analysis of competing-endogenous pathways (MACPath) in human cancers

Brain-state invariant thalamo-cortical coordination revealed by non-linear encoders

Haptic communication between humans is tuned by the hard or soft mechanics of interaction

Fluctuating Finite Element Analysis (FFEA): A continuum mechanics software tool for mesoscale simulation of biomolecules

Population dynamics of engineered underdominance and killer-rescue gene drives in the control of disease vectors

From correlation to causation: Estimating effective connectivity from zero-lag covariances of brain signals

Scabies in residential care homes: Modelling, inference and interventions for well-connected population sub-units

A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens

Dynamic combination of sensory and reward information under time pressure

Dynamic cues for whisker-based object localization: An analytical solution to vibration during active whisker touch

Modeling the dynamics of oligodendrocyte precursor cells and the genesis of gliomas

Astrocytic Kir4.1 channels and gap junctions account for spontaneous epileptic seizure

Bamgineer: Introduction of simulated allele-specific copy number variants into exome and targeted sequence data sets

SARNAclust: Semi-automatic detection of RNA protein binding motifs from immunoprecipitation data

An open source tool for automatic spatiotemporal assessment of calcium transients and local signal-close-to-noise' activity in calcium imaging data


Correction: Correlated receptor transport processes buffer single-cell heterogeneity

Correction: Effect of Ionic Diffusion on Extracellular Potentials in Neural Tissue

Correction: MAGPIE: Simplifying access and execution of computational models in the life sciences


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