Subject: PLOS Computational Biology Volume 13(6) June 2017 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: 8bit


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New Articles in PLOS Computational Biology

PUBLISHED: June 01, 2017 to June 30, 2017

Messages from ISCB

2017 ISCB Innovator Award: Aviv Regev

2017 ISCB Overton Prize awarded to Christoph Bock

2017 Outstanding Contributions to ISCB Award: Fran Lewitter

2017 ISCB Accomplishment by a Senior Scientist Award given to Pavel Pevzner


Good enough practices in scientific computing


Assessing computational genomics skills: Our experience in the H3ABioNet African bioinformatics network


A review of active learning approaches to experimental design for uncovering biological networks

A comprehensive overview and evaluation of circular RNA detection tools

Research Articles

Epidemiological and economic impact of pandemic influenza in Chicago: Priorities for vaccine interventions

Breakdown of local information processing may underlie isoflurane anesthesia effects

Network-assisted target identification for haploinsufficiency and homozygous profiling screens

A state space approach for piecewise-linear recurrent neural networks for identifying computational dynamics from neural measurements

A motor unit-based model of muscle fatigue

MMTF'An efficient file format for the transmission, visualization, and analysis of macromolecular structures

Reduction of multiscale stochastic biochemical reaction networks using exact moment derivation

Dynamic metabolic modeling of heterotrophic and mixotrophic microalgal growth on fermentative wastes

Mechanisms of generation of membrane potential resonance in a neuron with multiple resonant ionic currents

Fast and general tests of genetic interaction for genome-wide association studies

An integrated calcium imaging processing toolbox for the analysis of neuronal population dynamics

Mechanisms underlying a thalamocortical transformation during active tactile sensation

Mendel,MD: A user-friendly open-source web tool for analyzing WES and WGS in the diagnosis of patients with Mendelian disorders

Leveraging functional annotations in genetic risk prediction for human complex diseases

Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads

Temperature'amplitude coupling for stable biological rhythms at different temperatures

Metabolic network segmentation: A probabilistic graphical modeling approach to identify the sites and sequential order of metabolic regulation from non-targeted metabolomics data

Ribosome reinitiation can explain length-dependent translation of messenger RNA

Mitochondrial respiration and ROS emission during beta -oxidation in the heart: An experimental-computational study

Rosetta:MSF: a modular framework for multi-state computational protein design

Locking of correlated neural activity to ongoing oscillations

Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria

Histone posttranslational modifications predict specific alternative exon subtypes in mammalian brain

GINOM: A statistical framework for assessing interval overlap of multiple genomic features

Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE

Robust transmission of rate coding in the inhibitory Purkinje cell to cerebellar nuclei pathway in awake mice

Inferring repeat-protein energetics from evolutionary information

Sensory noise predicts divisive reshaping of receptive fields

In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis

A knowledge-based T2-statistic to perform pathway analysis for quantitative proteomic data

An efficient coding theory for a dynamic trajectory predicts non-uniform allocation of entorhinal grid cells to modules

Solving the influence maximization problem reveals regulatory organization of the yeast cell cycle

High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE

Transmembrane helical interactions in the CFTR channel pore

LASSIM'A network inference toolbox for genome-wide mechanistic modeling

A novel algorithm identifies stress-induced alterations in mitochondrial connectivity and inner membrane structure from confocal images

Olfactory learning without the mushroom bodies: Spiking neural network models of the honeybee lateral antennal lobe tract reveal its capacities in odour memory tasks of varied complexities

Brain network eigenmodes provide a robust and compact representation of the structural connectome in health and disease

Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome

Linking structure and activity in nonlinear spiking networks

Comorbidities in the diseasome are more apparent than real: What Bayesian filtering reveals about the comorbidities of depression

Low-dimensional spike rate models derived from networks of adaptive integrate-and-fire neurons: Comparison and implementation

MFPred: Rapid and accurate prediction of protein-peptide recognition multispecificity using self-consistent mean field theory

NetNorM: Capturing cancer-relevant information in somatic exome mutation data with gene networks for cancer stratification and prognosis

Optimal structure of metaplasticity for adaptive learning

Detecting similar binding pockets to enable systems polypharmacology

Landscape and variation of novel retroduplications in 26 human populations

Active Vertex Model for cell-resolution description of epithelial tissue mechanics

Independent regulation of gene expression level and noise by histone modifications


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