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New Articles in PLOS Computational Biology

PUBLISHED: February 01, 2017 to February 28, 2017


Ten Simple Rules for Developing a Successful Research Proposal in Brazil

Ten Simple Rules on How to Organize a Scientific Retreat

Research Articles

Fundamental Activity Constraints Lead to Specific Interpretations of the Connectome

A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations

Correlation-based model of artificially induced plasticity in motor cortex by a bidirectional brain-computer interface

Genome composition and phylogeny of microbes predict their co-occurrence in the environment

Effects of FGFR2 kinase activation loop dynamics on catalytic activity

Dynamic Maternal Gradients Control Timing and Shift-Rates for Drosophila Gap Gene Expression

Early and Real-Time Detection of Seasonal Influenza Onset

Insect Bio-inspired Neural Network Provides New Evidence on How Simple Feature Detectors Can Enable Complex Visual Generalization and Stimulus Location Invariance in the Miniature Brain of Honeybees

ASPASIA: A toolkit for evaluating the effects of biological interventions on SBML model behaviour

Unifying view of mechanical and functional hotspots across class A GPCRs

Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective

Data-driven reverse engineering of signaling pathways using ensembles of dynamic models

Multiscale mutation clustering algorithm identifies pan-cancer mutational clusters associated with pathway-level changes in gene expression

Bayesian phylogeography of influenza A/H3N2 for the 2014-15 season in the United States using three frameworks of ancestral state reconstruction

Accuracy Maximization Analysis for Sensory-Perceptual Tasks: Computational Improvements, Filter Robustness, and Coding Advantages for Scaled Additive Noise

Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells

A quantitative model for the rate-limiting process of UGA alternative assignments to stop and selenocysteine codons

Predicting Structure-Function Relations and Survival following Surgical and Bronchoscopic Lung Volume Reduction Treatment of Emphysema

Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control

Representing high throughput expression profiles via perturbation barcodes reveals compound targets

An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins

Human mobility and the spatial transmission of influenza in the United States

Metabolic regulation is sufficient for global and robust coordination of glucose uptake, catabolism, energy production and growth in Escherichia coli

Computational identification of the selenocysteine tRNA (tRNASec) in genomes

Spatial separation of two different pathways accounting for the generation of calcium signals in astrocytes

Elucidation of molecular kinetic schemes from macroscopic traces using system identification

Co-emergence of multi-scale cortical activities of irregular firing, oscillations and avalanches achieves cost-efficient information capacity

Comparing individual-based approaches to modelling the self-organization of multicellular tissues

Conformational diversity analysis reveals three functional mechanisms in proteins

Mathematical models of tissue stem and transit target cell divisions and the risk of radiation- or smoking-associated cancer

Depth-dependent flow and pressure characteristics in cortical microvascular networks

A mathematical model of calcium dynamics in HSY cells

Quantifying the Value of Perfect Information in Emergency Vaccination Campaigns

Testing the limits of gradient sensing

A Causal Inference Model Explains Perception of the McGurk Effect and Other Incongruent Audiovisual Speech

Optimality principles reveal a complex interplay of intermediate toxicity and kinetic efficiency in the regulation of prokaryotic metabolism

graph-GPA: A graphical model for prioritizing GWAS results and investigating pleiotropic architecture

Two dynamic regimes in the human gut microbiome

Metacoder: An R package for visualization and manipulation of community taxonomic diversity data

ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding

Mindboggling morphometry of human brains

Imputation for transcription factor binding predictions based on deep learning

On the stability and dynamics of stochastic spiking neuron models: Nonlinear Hawkes process and point process GLMs

Modeling of the axon membrane skeleton structure and implications for its mechanical properties

The genotype-phenotype map of an evolving digital organism

The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt


Correction: When Optimal Feedback Control Is Not Enough: Feedforward Strategies Are Required for Optimal Control with Active Sensing

Correction: Emergence of Slow-Switching Assemblies in Structured Neuronal Networks

Correction: Transcriptional Dynamics Reveal Critical Roles for Non-coding RNAs in the Immediate-Early Response

Correction: Psychotic Experiences and Overhasty Inferences Are Related to Maladaptive Learning

Correction: Behavioral Modeling of Human Choices Reveals Dissociable Effects of Physical Effort and Temporal Delay on Reward Devaluation


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