This Primer discusses how the economic valuation of ecosystem services can be used to choose sites for either land conservation or development, highlighting a recent study in PLOS Biology. Read the associated Research Article here.
This Primer discusses a recent study which suggests that objects in visual scenes are sampled one-by-one rather than in parallel; this sampling is reflected by modulations of neuronal ~10-Hz oscillations. Read the associated Research Article here.
This Primer discusses recent findings which indicate that bacteria can hijack the function of the anti-bacterial lymphocytes known as mucosa-associated invariant T (MAIT) cells and leave them dead in the water. Read the associated Research Article here.
In this Research Matters article, Andrew Read recalls how an analysis of incest in wasps revealed a way to improve human well-being.
Data science in biomedicine is a field where the demand for the workforce far outweighs the supply; this article describes how the US National Institutes of Health has set about addressing the situation.
Issues associated with consent and the control of biomedical research samples in the context of biobanking continue to create significant legal and public perception challenges¦ and things could get worse.
This Community Page article tells you how to build your own fluorescence microscope and behavioural rig for less than 100 Euros using 3-D printed parts and off-the-shelf electronics.
Tau protein binds tRNA in living cells, and under physiological conditions reversibly condenses to form complex liquid droplets that may be precursors for the formation of tau fibrils found in neurodegenerative diseases.
Hair follicle development involves establishing a hierarchy of patterning systems, whereby a patterning process driven by cell movement is subordinated to a signal-based reaction-diffusion mechanism.
A new model, in which four simple rules can produce a mammalian embryo and explain scaling, ensures developmental robustness while allowing evolution to play with stochasticity.
A bifunctional snake venom protein from the Malayan pit viper Calloselasma rhodostoma blocks collagen mediated platelet aggregation, undergoing dramatic conformational changes as it binds alpha 2beta 1 integrin.
The receptor tyrosine kinase EphB undergoes ligand-dependent extracellular phosphorylation to regulate NMDA receptor synaptic localization and pathological pain in mice.
A study of 30,000 species reveals that faster changing seed sizes are associated with increased rates of species formation across the angiosperm tree of life.
A pan-tropical study reveals the spatial economic trade-offs between agricultural conversion and the loss of multiple ecosystem services, revealing opportunity and challenge areas for tropical conservation.
A computational model of how neuronal population activity is translated into a metabolic response (the fMRI Blood Oxygen Level Dependent, or BOLD, signal) or an electrical measure (the ECoG local field potential), shows that the former emphasizes the total level of neuronal activity while the latter emphasizes neuronal synchrony.
Comparisons between two tardigrade species using high-quality genome sequences reveals a diversity of mechanisms for anhydrobiosis, a minor but important role for horizontal gene transfer, and unexpected evolutionary relationships to other phyla.
Combined single-cell morphometry and transcriptomics reveal that hematopoietic stem cells undergo a random fluctuating phase of variable length before committing to a given fate.
Anesthetic exposure in early childhood may cause lasting cognitive deficits. This study shows that isoflurane acts on the mTOR pathway to cause dendritic spine loss and learning deficits in mice.
Methods and Resources
ChemNetDB is a systematic, terminologically consistent open-access resource for the multi-scale neurochemical connectome of the rat brain, containing data from 34,464 animals.