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Current Issue of Nature


Current Issue : Nature

Current Issue

Volume 542 Number 7641 pp271-386

16 February 2017

About the cover

The cover shows women threshing quinoa in Peru’s highlands. In this issue, Mark Tester and colleagues report a reference genome for quinoa (Chenopodium quinoa), a highly nutritious crop that can grow under a wide range of environmental conditions. Long-read sequencing combined with optical, chromosome-contact and genetic maps was used to generate the allotetraploid genome. The authors also sequenced the genomes of additional diploid and tetraploid Chenopodium species, characterizing genetic diversity and the evolution of sub-genomes in the crop. In the process, Tester and colleagues identified a transcription factor that regulates the biosynthesis of bitter-tasting saponins in quinoa, as well as markers that might be used to develop sweet commercial varieties. Cover image: Lynn Johnson/National Geographic Creative.

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      • The genome of Chenopodium quinoaOpen

        • David E. Jarvis
        • Yung Shwen Ho
        • Damien J. Lightfoot
        • Sandra M. Schmöckel
        • Bo Li
        • Theo J. A. Borm
        • Hajime Ohyanagi
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        • Takashi Gojobori
        • C. Gerard van der Linden
        • Eibertus N. van Loo
        • Eric N. Jellen
        • Peter J. Maughan
        • Mark Tester

        Constructing a reference genome for quinoa (Chenopodium quinoa) allows for genetic diversity during the evolution of sub-genomes in quinoa to be characterized and markers that may be used to develop sweet commercial varieties are identified.

        See also
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        • Papia Ghosh
        • Virginia Giuliani
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        • Prasenjit Dey
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        • Michael G. Goggins
        • Laura D. Wood
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        • Anirban Maitra
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        • Andrea Viale
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        • Giulio F. Draetta
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        Depletion of Smarcb1 activates the Myc network of signalling cascades, increasing protein metabolism and activation of survival pathways allowing highly aggressive Kras-independent pancreatic cancer cells to develop.

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        Adult neurons from Caenorhabditis elegans can extrude large membrane-surrounded vesicles, known as exophers, containing protein aggregates and dysfunctional organelles that threaten neuronal homeostasis.